10.1001/jama.1991.03460010094039
At a Glance What changed in April On 15 April 2026 the FDA updated its Section 503A bulk drug substances list, removing 12 peptides from Category 2 the designation the agency uses for substances it considers to raise significant safety concerns for compounding
Cagrilintide + Retatrutide Storage & Handling Storage Reference (Both Compounds) State Lyophilized (long-term) Cagrilintide -4 F (-20 C), 12+ months Retatrutide -4 F (-20 C), 12+ months State Lyophilized (short-term) Cagrilintide 35.6-46.4 F (2-8 C), several months Retatrutide 35.6-46.4 F (2-8 C), several months State Reconstituted (liquid) Cagrilintide 35.6-46.4 F (2-8 C), 28-30 days Retatrutide 35.6-46.4 F (2-8 C), 28-30 days State Color when reconstituted Cagrilintide Clear, colorless Retatrutide Clear, colorless State Shake
Statements Author contributions YW: Writing original draft
doi: 10.1016/j.joca.2024.02.003 9
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